The Effect of Aloe Vera and Eucalyptol Oil on the Development of Tooth Germs in Albino Rats: A Histological and Histochemical Study

Document Type : Original Article

Authors

1 Demonstrator of Oral and Dental Biology, AL-Azhar University for Girls.

2 Associate Professor of Oral and Dental Biology Faculty of Dental Medicine, AL-Azhar University for Girls.

3 Lecturer of Oral and Dental Biology Faculty of Dental Medicine AL-Azhar University for Girls.

Abstract

Tooth development or odontogenesis is a very complex process involving many growth factors and transcription factors of genes to ensure an ordered and controlled development of tooth germs. Increasing use of herbal remedies by mothers during pregnancy to avoid side effects of medical drugs may cause systemic and local effects on tooth development. In this study 50 pregnant rats were used, G1 control, GII eucalyptol oil vapour, GIII aloe vera. Offsprings were sacrificed at 1stday and 5th day, the specimens were obtained by serial sagittal sections and stained with (H&E) and Mercuric Bromophenol Blue (special stain). Administration of these herbal medicine during pregnancy result in adverse effects on tooth germ development of the offspring, delay tooth formation, change the thickness of the constituent layers of the teeth and disturbance and altered minerlization of enamel and dentin layers.

Keywords

Al-Azhar Dental Journal for Girls
Volume 3, Issue 3
July 2016
Pages 193-200

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