Pulp Tissue Response to Platelets Rich Plasma, Platelets Rich Fibrin and Mineral Trioxide Aggregate as Pulp Capping Materials

Document Type : Original Article

Authors

1 Assistant lecturer of operative dentistry, Faculty of dental medicine, Misr University for Science and Technology MUST, Cairo, Egypt

2 Professor of operative dentistry, Faculty of dental medicine for Girls, Al-Azhar University, Cairo, Egypt.

3 Professor and head of operative dentistry, Faculty of dental medicine for Girls, Al-Azhar University, Cairo, Egypt

4 Professor of Surgery, Anesthesiology & Radiology, Faculty of veterinary Medicine, Cairo University, Egypt

Abstract

 Purpose: to evaluate the biological response of the dog teeth to Platelets Rich plasma (PRP), Platelets Rich fibrin (PRF) and mineral trioxide aggregate (MTA) as pulp capping materials. Material and Methods: A total of 90 teeth of dogs were included. Class V cavities were prepared. Pulp exposure was performed in the middle of cavity floor. The teeth were divided into three groups of 30 teeth according to the material used; A1: PRP, A2: PRF and A3: MTA. Glass ionomer restoration was applied as restoration for the cavities. The tissue response to the materials was assessed at three different post-operative periods of 7, 30, 60 days. The animal was sacrificed. Histomorphometric analysis was performed. Result: the results showed high inflammatory cells count at 7 days for all treated groups; PRP treated teeth showed the highest at 7 days, while PRF showed the least. At 1 and 2 months postoperatively no significant difference was found between all the treated groups. For dentin bridge scores; there was no significant difference between all the materials at 7 days and 1 month. At 2 months; the MTA treated teeth recorded the greatest dentin bridge score as compared to all treated teeth. As for integrity of odontoblast score; results showed no significant difference between different materials at 7 days and 1 month. The MTA treated teeth showed the highest score as compared to PRP and PRF at 2 months. Conclusion: Among the three different materials, PRP and PRF appeared to be promising pulp capping agents.

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Al-Azhar Dental Journal for Girls
Volume 8, Issue 4
issue4 October-Restorative Dentistry issue (Removable Prosthodontics, Fixed Prosthodontics, Endodontics, Dental Biomaterials, Operative Dentistry)
October 2021
Pages 561-570

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