Effect of Lepidium Sativum Gel as an Adjunct to Non- Surgical Treatment in Management of Periodontitis Patients Stage (II, III) and Grade (A, B)

Document Type : Original Article

Authors

1 Dentist at Faculty of Oral and Dental Medicine 6 October University, Cairo, Egypt

2 Professor of Oral Medicine, Periodontology, Oral Diagnosis and Radiology Faculty of Dental Medicine for Girls’ - Al-Azhar University, Cairo, Egypt.

3 Lecturer of Pharmaceutic, Faculty of Pharmacy’ - Al-Azhar University, Cairo, Egypt

4 Lecturer of Oral Medicine, Periodontology, Oral Diagnosis and Radiology Faculty of Dental Medicine for Girls-Al-Azhar University, Cairo, Egypt.

Abstract

Purpose: The current study was conducted to elaborate the clinical and transforming growth factor beta biomarker effect of local application of lepidium sativum gel as an adjunct to scaling and root planing in the therapeutic management of periodontitis patients stage( II, III) and grade(A, B). Subjects and Methods: The current study was conducted on twenty patients were selected in this study with stage (II, III) and grade (A, B) periodontitis. Patients were randomly divided into two group’s ten subjects on each. Group A: (control group) were treated with scaling and root planing alone, group B: (study group) were treated with scaling and root planing with local delivery of lepidium sativum gel. Results: study group showed a significant increase in the clinical parameter like clinical attachment level (CAL), probing depth (PD), bleeding on probing (BOP) and plaque index (PI). Clinical parameters were recorded after one month and three months, transforming growth factor beta biomarker level after one week and four weeks in comparison with control group follow up. Conclusion: Adjunctive use of lepidium sativum with non-surgical therapy showed an improvement in the treatment outcome of periodontitis patient’s stage (II, III) and grade (A, B).

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