Effect of Different Concentrations of Double Antibiotics used in Regenerative Endodontic on MicroHardness and Fracture Resistance of Radicular Dentin

Document Type : Original Article

Authors

1 Dentist at Ministry of Health, Egypt.

2 Professor of Endodontic department Faculty of Dental Medicine for Girls Al-Azhar University, Cairo, Egypt.

3 Lecturer of Endodontic department Faculty of Dental Medicine for Girls AL-Azhar University, Cairo, Egypt.

Abstract

Purpose: to show the effect of different concentrations of double antibiotics paste (DAP) 1, 0.1,0 .01mg/ml used in regenerative endodontic on microhardness and fracture resistance of radicular dentin. Material and methods: Forty single rooted teeth were prepared and randomized into three groups according to DAP concentration (10 samples each) and ten samples were availed as control group. Group I: root canal contained 1mg /ml DAP. Group II: root canal contained 0.1mg /ml DAP. Group III: root canal contained 0.01 mg/ml DAP. Samples were stored at 37 0c with 100% humidity for three weeks then DAP was removed by irrigation with 1.5% NaoCl followed by 17 % EDTA, finally flushed with distilled water. After removal of DAP, each tooth was decoronated at the level 0.5 mm radicular to the facial cementoenamel junction with isomet saw under water cooling. Two root cylinders were attained, one cylinder for fracture resistance assessment and the other cylinder for microhardness assessment. Results: For microhardness test, there was a statistically significant difference among different concentrations of DAP (P≤ 0.05).The highest mean value of microhardness was recorded in group III (DAP 0.01mg/ml). For fracture resistance test, there was statistically significant difference among different concentration of DAP (P≤0.05), group III (DAP 0.01mg/ml) showing the highest mean value of fracture resistance. However group III (DAP 0.01mg/ml) showing no significant difference with control group. Conclusion: Lower concentration of double antibiotic (0.01mg/ml) increases microhardness and fracture resistance of radicular dentin in revascularization procedure

Keywords

Main Subjects